Hexokinase activity and aging.
Bone marrow mesenchymal stem
cells (MSC) were cultured in vitro.
Early and late passage MSC were
harvested for enzyme assay. The
study shows that hexokinase
activity is increased upon repeated
cell passages in vitro.
Welcome to BMR
- Streamlining Laboratory Medicine -
Biomedical Research Service & Clinical
Application is affiliated with the School of
Medicine and Biomedical Sciences,
University at Buffalo. The center produces
high-quality, cost-effective research and
diagnostic reagents for the broad life
science and clinical communities, and
promotes collaborative translational
research. Please send your inquiry to:
Dr. Techung Lee
Department of Biochemistry
& Department of Biomedical Engineering
University at Buffalo
Tel: (716) 829-3106
An easy assay of fatty acid
oxidation capacity. Mice were fed
methionine-choline deficient diet
(MCDD) for 14 weeks. Heart tissues
were homogenized and FAO
activities were assayed by the FAO
Biomedical Research Service
& Clinical Application
An enzyme marker of clinical utility.
Mice were fed methionine-choline
deficient diet (MCDD) for 6 weeks.
Liver tissues were homogenized
and PGI activities were assayed by
the PGI Assay kit.
Here are some of the
pharmaceutical and biotech
companies we have proudly
served over the years:
Discovering IMPDH inhibitors.
HeLa cells were treated with DMSO
(control) and 10 uM mycophenolic
acid (MPA) for 24 hours, following
which cells were harvested and
IMPDH activity was measured
using the IMPDH assay kit.
Discovering inhibitor of MMP2/9.
Prinomastat, a potent MMP
inhibitor, reduces the activity of
MMP2/9 by ~70% at 2.5 nM using
the assay kit.