Biomedical Research Service

Bone marrow mesenchymal
stem cells (MSC) were
cultured in vitro. Early and
late passage MSC were
harvested for enzyme assay.
The study shows that
hexokinase activity is
increased during cellular
senescence.

Welcome to BMR
- Streamlining Laboratory Medicine -

BMR is affiliated with the University at
Buffalo. The center produces
high-quality, cost-effective reagents for
the broad life science and clinical
medicine communities, and promotes
collaborative translational research. Our
W9 form is available for vendor setup.

Please send your inquiry to:
Dr. Techung Lee
Director
Department of Biochemistry
& Department of Biomedical Engineering
University at Buffalo
Email: chunglee@buffalo.edu
Tel/Fax: (716) 829-3106

Mice were fed methionine- and
choline-deficient (MCD) diet for
14 weeks. Heart tissues were
homogenized and FAO
activities were assayed. The
data indicate that cardiac fatty
acid oxidation capacity can be
compromised in the fatty acid
model.

Biomedical Research Service
& Clinical Application

Mice were fed methionine- and
choline-deficient (MCD) diet for 6
weeks. Liver tissues were
homogenized and PGI activities
were assayed. The data show that
the fatty liver exhibits increased
PGI activities. In addition, the
serum level of PGI activity is also
increased in the fatty liver model.

Site Map

Alphabetical
Listing

Ethanol Metabolism
Alcohol dehydrogenas e (ADH)
Aldehyde dehydrogenas e (ALDH)
Ethanol

Here are some of the pharmaceutical and biotech
companies we have served over the years:

PGI Assay

Fatty Acid Oxidation

Hexokinase Assay

IMPDH Assay

HeLa cells were treated with
DMSO (control) and 10 uM
mycophenolic acid (MPA) for
24 hours, following which cells
were harvested and IMPDH
activity was measured. The
IMPDH activity assay kit has
been used for drug discovery
application.

MMP2/9 Assay

Matrix metalloproteinases (MMPs)
play important roles in ECM
remodeling. Prinomastat, a potent
MMP inhibitor, reduces the activity
of MMP2/9 by ~70% at 2.5 nM
using the convenient MMP2/9
liquid assay kit.

Nagalase Assay

Skeletal muscle tissues were
collected from normal
hamster (F1B strain) and
dystrophic strain (TO2), and
homogenized. Muslce
Nagalase enzyme activity
was measured, showing that
muscular dystrophy is
associated with increased
Nagalase enzyme activity.