GST (Glutathione S-transferase) Price
BACKGROUND: Many recombinant proteins are expressed as GST-fusion proteins to facilitate purification. The recombinant GST protein is encoded
by the parasitic Schistosoma japonicum glutathione S-transferase gene. The parasite GST protein shows ~60% homogy with class Mu isozymes of
mammalian GST (EC 2.5.1.18). The mammalian GST super family consists of four classes: Alpha, Mu, Pi, and Theta. GST catalyzes the conjugation
of reduced glutathione to electrophiles on many substrates, thus detoxifying endogenous compounds such as lipid peroxides. The recombinant GST
can be used as a negative control for recombinant growth factors expressed as GST fusion proteins. The C-terminal end of the protein harbors an
engineered thrombin cleavage site and a protein kinase A (PKA) phosphorylation site. The protein can therefore be radioactively labeled with
32P-g-ATP and PKA. The product is for research use only.
BACKGROUND: Many recombinant proteins are expressed as GST-fusion proteins to facilitate purification. The recombinant GST protein is encoded
by the parasitic Schistosoma japonicum glutathione S-transferase gene. The parasite GST protein shows ~60% homogy with class Mu isozymes of
mammalian GST (EC 2.5.1.18). The mammalian GST super family consists of four classes: Alpha, Mu, Pi, and Theta. GST catalyzes the conjugation
of reduced glutathione to electrophiles on many substrates, thus detoxifying endogenous compounds such as lipid peroxides. The recombinant GST
can be used as a negative control for recombinant growth factors expressed as GST fusion proteins. The C-terminal end of the protein harbors an
engineered thrombin cleavage site and a protein kinase A (PKA) phosphorylation site. The protein can therefore be radioactively labeled with
32P-g-ATP and PKA. The product is for research use only.
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Biomedical Research Service
& Clinical Application
& Clinical Application