Lipid Peroxidation (MDA) Assay Kit                                                                                                                                                             Price

Product Description: Cells exposed to oxidative stress accumulate a complex profile of aldehydes which are derived from the decomposition of
lipid hydroperoxides (Free Radical Biology & Medicine 7:197,1989). In contrast to free radicals, also caused by oxidative stress, the aldehydes
are more stable and tend to diffuse over large distances both intracellularly and extracellularly. Thus, profound cytotoxic and genotoxic effects
are associated with these aldehyde products, and the determination of aldehydes is of wide interests. Malondialdehyde (MDA) and MDA-like
substances are by far the most abundant lipid peroxidation products. High levels of MDA and MDA-like substances are produced during the
oxidation of low density lipoprotein. Although HPLC can be used to measure the production of these lipid peroxidation products, the analysis of
MDA by the classical TBA (2-thiobarbituric acid) test remains a simple, reliable, and useful method applicable in most if not every laboratory (J.
Lipid Res. 28:495,1987). Our Lipid Peroxidation Assay Kit is formulated based on the TBA method. The kit is stable for one year if stored and
handled properly.

Kit Components:

TBA: 0.75 g, store at room temperature
MDA Assay Solution: 100 ml, store at room temperature

MSDS: NaOH, 2-thiobarbituric acid, TCA

Related kits: Cell Injury Assay, Peroxide Assay, Nitric Oxide Assay, Cell Viability Assay, Free Thiol Assay

Citation:
Yoo et al
Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer’s Disease
ANTIOXIDANTS & REDOX SIGNALING 12:819-827, 2010

Neuron 82, 195–207, April 2, 2014

Transplantation 87:1275, 2009

Mol Cell Biochem 321:45, 2009
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Normal hamster (F1B strain) and
cardiomyopathic hamster (TO2 strain)
were used in the study. TO2 hamsters
received intramuscular injection of
mesenchymal stem cells. The study
shows the dystrophic muscle contains
elevated levels of MDA, which could be
reduced to normal levels by the MSC
therapy.
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